inb4 old
Expectations and wild guesses:
Microsoft
Skyrim
Resident Evil remake.
Halo 1 remake, to come with game adaptation of the First Strike novel.
Mass Effect 3's Kinect abilities to be shown off.
Forza 4 to be drooled over by the people who are not me.
Modern Warfare 3 footage and a completely new CoD game revealed.
Gears 3, yawn.
XCOM
S.T.A.L.K.E.R. 2
Skype for Xbox Live
Some new 1 Vs. 100-style game.
Raising the Friend Limit
Project Kingdoms
Saints Row: The Third
360 Price Drop
Battlefield 3
XBLA games.
Faybul IV
Devil's Third
Prey 2
Rare Kinect Collection, complete with new Viva Piñata, Banjo and Conker games.
Sony
Arkham City
Careful avoidance of the word "hack".
Kevin Butler.
Twisted Metal
Prototype 2
Infamous 2
Ratchet & Clank: All 4 One
Kingdom Hearts for PS3 and NGP
Killzone 4
Starhawk
Cross-Game Voice Chat Pigs flying
Uncharted 3
Dark Souls
Move Price Drop
Tekken.
Sly Cooper HD Collection
Shadow of the Colossus remake footage
Lots more NGP stuff. LittleBigPlanet, MGS, Tekken, PAIN, Valkyria Chronicles, Final Fantasy, Motorstorm.
Splinter Cell HD Collection
Devil May Cry 5
Rockstar HD Collection. Revolver, Bully, Manhunt, GTA, Max Payne all possible inclusions.
PSN Titles.
Crash Bandicoot HD Collection
TRANSFARRING.
God of War IV
Prince of Persia
The Darkness II
Splimetitters HD Collection
The Agent
Granny Turismo
Nintendo
Lots of Project Cafe stuff. Metroid, Zelda, Mario, Kingdom Hearts, Kirby, Kid Icarus, Animal Crossing, Final Fantasy, SSB and more.
Pikmin
Skyward Sword
Just Dance 3
Red Steel III
3DS stuff.
Silent Hill
Dead Space
SSX
Super Monkey Balls
No More Heroes 3
Soul Calibur
Pokémon RSEmakes.
Spyro
Shaun White
Sonic
Star Wars Battlefront III
Hitman
GTA V
New Reggie meme.
EA
Mass Effect 3
Battlefield 3
Battlefield 2143
Burnout 6
New Need for Speed title.
FIFA 12
Madden.
Star Wars: The Old Republic
Social Networking games.
The Sims
Black & White III
Black II
Command & Conquer
EA Wii/Cafe titles
New IP
Army of Two? Dragon Age? Dante's Inferno? Skate 4? Spore 2? New Medal of Honor or Mirror's Edge? Fairly certain a new sequel or three will be revealed.
Gun Club Rewards
Ubisoft
Call of Juarez
Assassin's Creed: Revelations
I Am Alive
Driver
Just Dance 3
Trackmania for consoles
Rayman Origins
Ghost Recon: Future Soldier
Splinter Cell
EndWar 2
Beyond Good and Evil 2
Far Cry 3
Uplay Rewards
Brothers in Arms
Rainbow Six
From Dust
Rocksmith
Obviously not all of this will happen. Just wild guessing mainly.